Apply

Horizon Europe - Cluster 1: Health

Cluster 1 focuses on improving the health and well-being of people of all ages by advancing research and developing innovative healthcare solutions by preventing, diagnosing, monitoring, treating, and curing illnesses. Among the aims of this cluster are promoting healthy living, creating stronger and more sustainable healthcare systems, and empowering patients in advocating for and managing their care. Key areas of intervention include health throughout the lifespan, social and environmental determinants of health, rare and chronic diseases (both infectious and non-communicable), digital health solutions, and health systems.

If you are interested in learning more about Cluster 1 funding opportunities:

Please contact the International Research Facilitator

 

European Commision website for Cluster 1: Health
Cluster 1 Webinar Recording by the Delegation of the European Union to Canada (YouTube)
Cluster 1 Work Programme for 2025 (PDF)

Cluster 1 Funding Calls

The following opportunities are currently available for Cluster 1. Please click on the program code for a direct link to the funding call in the EU Funding and Tenders Portal.

Destination1

Competition Code

Competition Name

Action2

Expected Funding

ORS Internal Deadline

Funder Deadline

Staying healthy in a rapidly changing society HORIZON-HLTH-2025-03-STAYHLTH-01-two-stage Improving the quality of life of persons with intellectual
disabilities and their families
RIA  €6-8 mil. x 5 projects Stage 1: August 25, 2025
Stage 2: March 25, 2026
Stage 1: September 15, 2025
Stage 2: April 15, 2026
Living and working in a health-promoting
environment
HORIZON-HLTH-2025-03-ENVHLTH-01-two-stage The impact of pollution on the development and progression of
brain diseases and disorders
RIA  €6-7 mil. x 6 projects Stage 1: August 25, 2025
Stage 2: March 25, 2026
Stage 1: September 15, 2025
Stage 2: April 15, 2026
HORIZON-HLTH-2025-03-ENVHLTH-02-two-stage Advancing knowledge on the impacts of micro- and nanoplastics
on human health
RIA  €7-8 mil. x 5 projects Stage 1: August 25, 2025
Stage 2: March 25, 2026
Stage 1: September 15, 2025
Stage 2: April 15, 2026
Tackling diseases and reducing disease
burden
HORIZON-HLTH-2025-01-DISEASE-01 Testing safety and efficacy of phage therapy for the treatment of
antibiotic-resistant bacterial infections
RIA ~ €15 mil. x 3 projects August 25, 2025 September 15, 2025
HORIZON-HLTH-2025-03-DISEASE-02-two-stage Advancing innovative interventions for mental, behavioural, and
neurodevelopmental disorders
RIA  €6-8 mil. x 7 projects Stage 1: August 25, 2025
Stage 2: March 25, 2026
Stage 1: September 15, 2025
Stage 2: April 15, 2026
HORIZON-HLTH-2025-01-DISEASE-03 Development of antibodies and antibody-derived proteins for
the prevention and treatmentof infectious diseases with
epidemic potential
RIA ~ €10 mil. x 5 projects August 25, 2025 September 15, 2025
HORIZON-HLTH-2025-01-DISEASE-04 Leveraging artificial intelligence for pandemic preparedness
and response
RIA  €6-8 mil. x 5 projects August 25, 2025 September 15, 2025
HORIZON-HLTH-2025-01-DISEASE-05 Support for the functioning of the Global Research Collaboration
for Infectious Disease Preparedness (GLoPID-R)
CSA ~ €2 mil. x 1 project August 25, 2025 September 15, 2025
HORIZON-HLTH-2025-01-DISEASE-06 Implementation research addressing strategies to strengthen
health systems for equitable high-quality care and health
outcomes in the ocntext of non-communicable diseases (GACD)
RIA  €3-4 mil. x 5 projects August 25, 2025 September 15, 2025
HORIZON-HLTH-2025-01-DISEASE-07 Tackling high-burden for patients and under-researched medical
conditions
RIA ~ €6 mil. x 5 projects August 25, 2025 September 15, 2025
Ensuring equal access to innovative,
sustainable, and high-quality healthcare
HORIZON-HLTH-2025-01-CARE-01 End-user driven application of Generative Artificial Intelligence
models in healthcare (GenAI4EU)
RIA ~ €15-20 mil. x 2 projects August 25, 2025 September 15, 2025
Developing and using new tools, technologies,
and digital solutions for a healthy society
HORIZON-HLTH-2025-01-TOOL-01 Enhancing cell therapies with genomic techniques RIA ~ €8-10 mil. x 5 projects August 25, 2025 September 15, 2025
HORIZON-HLTH-2025-01-TOOL-02 Advancing cell secretome-based therapies RIA ~ €9-13 mil. x 3 projects August 25, 2025 September 15, 2025
HORIZON-HLTH-2025-01-TOOL-03 Leveraging multimodal data to advance Generative
Artificial Intelligence applicability in biomedical research (GenAI4EU)
RIA ~ €15-17 mil. x 3 projects August 25, 2025 September 15, 2025
HORIZON-HLTH-2025-01-TOOL-05 Boosting the translation of biotech research into innovative health
therapies
RIA  €4-8 mil. x 10 projects August 25, 2025 September 15, 2025
Maintaining an innovative, sustainable,
and competitive EU health industry
HORIZON-HLTH-2025-01-IND-01 Optimising the manufacturing of Advanced Therapy Medicinal
Products (ATMPs)
IA  €6-8 mil. x 5 projects August 25, 2025 September 15, 2025
HORIZON-HLTH-2025-01-IND-02 Digitalisation of conformity assessment procedures of medical
devices and in vitro diagnostic medical devices
CSA ~ €4 mil. x  1 project August 25, 2025 September 15, 2025
HORIZON-HLTH-2025-03-IND-03-two-stage Facilitating the conduct of multinational clinical studies
of oprhan devices and/or of highly innovative ("breakthrough") devices
RIA  €6-8 mil. x 5 projects Stage 1: August 25, 2025
Stage 2: March 25, 2026
Stage 1: September 15, 2025
Stage 2: April 15, 2026

1”Destinations” represent the expected impact of projects within this group. More information is available in the Work Programme document in the Resources section above.
2”Action” describes the types of activities and their aims. Where applicable, these may correspond with a range of Technology Readiness Levels (TRLs).
RIA – Research and Innovation Actions. Where applicable, these often correspond with projects in the range of TRL 2-6.
IA – Innovation Actions. Where applicable, these often correspond with projects in the range of TRL 4-8.
CSA – Coordination and Support Actions. Actions contribute to Horizon Europe’s objectives by promoting collaboration, coordination of research and innovation activities, and knowledge exchange.

Upcoming and Recent Webinars

Spanish National Research Council (CSIC)

The Spanish National Research Council (CSIC) is hosting a webinar and seeking Canadian partners for health project calls, recently released in the 2025 Horizon Europe Work Programme for Cluster 1. The webinar is scheduled for June 4th and you can register using the following link: Webinar Registration - Zoom.

This webinar will include participation from Canada’s Cluster 1 National Contact Points and CSIC’s Cluster 1 Horizon Europe Leads. It will be a great opportunity to learn more about the funding opportunities within the Horizon Europe framework, Canadian NCPs and their role, timelines for 2025 and 2026 calls and strategies in preparing your pitches for collaborating with CSIC on these Cluster 1 Health project submissions.

Networking Opportunities

Spanish National Research Council (CSIC)

Spain’s National Research Council, CSIC, Horizon Europe’s SECOND most active participant seeks CANADIAN partners for the following seven health project calls which close on September 18, 2025.

Canadians are encouraged to email programas.europeos@csic.es to share one’s pitch for the call(s) of interest by June 11, 2025. Please consult the four-page Horizon Europe Support Document (XLSX) and reach out to Canada’s National Contact Points (NCP) in copy for help in your efforts.

The Spanish National Research Council (CSIC) is Spain’s largest public research institution with over 16,000 research staff and ranks as the fourth most prominent public research organization in the European Union and seventh, globally. Operating under the Ministry of Science and Innovation while maintaining independent legal status, CSIC carries out research, innovation and training activities in all fields of knowledge and it plays a pivotal role in shaping scientific and technological policy, both in Spain and worldwide. CSIC is the SECOND most active participant in Horizon Europe based on total number of funded actions as of 2025, with 661 signed grants and a net EU contribution of EUR 298 million.