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Paul Levett

Clinical Microbiologist, BC Centre for Disease Control
PhD, DSc, (D)ABMM, FCCM, FAAM

Office: BCCDC, 655 West 12th Avenue, Vancouver, BC V5Z 4R4
E-mail: paul.levett@bccdc.ca

Research interests
Applied Public Health Microbiology, Leptospirosis

Qualifications

  • BSc (Hons), PhD, DSc
  • Diplomate of the American Board of Medical Microbiology
  • Fellow of the Canadian College of Microbiologists
  • Fellow of the American Academy of Microbiologists

Current research

I have a wide range of research interests, concentrating on diagnostic and epidemiological studies of zoonoses, for example leptospirosis and West Nile virus

Selected recent publications

Levett PN, Fonseca K, Tsang RS, Kadkhoda K, Serhir B, Radons SM, Morshed M (2015) Canadian Public Health Laboratory Network laboratory guidelines for the use of serological tests (excluding point-of-care tests) for the diagnosis of syphilis in Canada. Canadian Journal of Infectious Diseases and Medical Microbiology 26:6A-12A.

Hatchette TF, Drews SJ, Grudeski E, Booth T, Martineau C, Dust K, Garceau R, Gubbay J, Karnauchow T, Krajden M, Levett PN, Mazzulli T, McDonald RR, McNabb A, Mubareka S, Needle R, Petrich A, Richardson S, Rutherford C, Smieja M, Tellier R, Tipples G, LeBlanc JJ (2015) Detection of enterovirus D68 in Canadian laboratories. Journal of Clinical Microbiology 53:1748-51

Levett PN (2015) Systematics of Leptospiraceae. Current Topics in Microbiology and Immunology 387: 11-20.

Haake DA, Levett PN (2015) Leptospirosis in humans. Current Topics in Microbiology and Immunology 387: 65-97.

Thakur S, Levett PN, Horsman GB, Dillon JA (2014) Molecular epidemiology of Neisseria gonorrhoeae isolates from Saskatchewan, Canada: utility of NG-MAST in predicting antimicrobial susceptibility. Sexually Transmitted Infections 90:297-302.

Thakur S, Starnino S, Horsman GB, Levett PN, Dillon JA (2014) Unique combined penA/mtrR/porB mutations and NG-MAST strain types associated with MIC increases to ceftriaxone and cefixime in a “susceptible” Neisseria gonorrhoeae population. Journal of Antimicrobial Chemotherapy 69: 1510-1516.

Romero-Vivas CM, Thiry D, Rodríguez V, Calderón A, Arrieta G, Máttar S, Cuello M, Levett PN, Falconar AK (2013) Molecular serovar characterization of Leptospira isolates from animals and water in Colombia. Biomedica.33 Suppl 1:179-184.

Malloch L, Kadivar K, Putz J, Levett PN, Tang J, Hatchette TF, Kadkhoda K, Ng D, Ho J, Kim J (2013). Comparative evaluation of the Bio-Rad Geenius HIV-1/2 confirmatory assay and the Bio-Rad Multispot HIV-1/2 rapid test as an alternative differentiation assay for CLSI M53 algorithm-I. Journal of Clinical Virology 58 Suppl 1:e85-e91.

McDonald RR, Golding GR, Irvine J, Graham MR, Tyler S, Mulvey MR, Levett PN (2013). Draft genome sequence of methicillin-susceptible Staphylococcus aureus strain 06BA18369, a pathogen associated with skin and soft tissue infections in Northern Saskatchewan, Canada. Genome Announcements 1:e00389-00313-e00389-00313.

McDonald RR, Golding GR, Irvine J, Graham MR, Tyler S, Mulvey MR, Levett PN (2013). Draft genome sequence of Streptococcus pyogenes strain 06BA18369, a human pathogen associated with skin and soft tissue infections in Northern Canada. Genome Announcements 1:e00387-00313-e00387-00313.

Vidovic S, Tsoi S, Medihala P, Liu J, Wylie JL, Levett PN, Korber DR (2013). Molecular and antimicrobial susceptibility analyses distinguish clinical from bovine Escherichia coli O157 strains. Journal of Clinical Microbiology 51:2082-2088.

Smythe L, Adler B, Hartskeerl RA, Galloway RL, Turenne CY, Levett PN (2013) Classification of Leptospira genomospecies 1, genomospecies 3, genomospecies 4 and genomospecies 5 as Leptospira alstonii sp. nov., Leptospira vanthielii sp. nov., Leptospira terpstrae sp. nov., Leptospira yanagawae sp. nov., respectively. International Journal of Systematic and Evolutionary Microbiology 63: 1859-1862.

Boa TT, Rahube TO, Fremaux B, Levett PN, Yost CK (2013) Prevalence of methicillin-resistant staphylococci species isolated from computer keyboards located in secondary and postsecondary schools. Journal of Environmental Health 75: 50-58.

Romero-Vivas CM, Cuello-Pérez M, Agudelo-Flórez P, Thiry D, Levett PN, Falconar AK (2013) Cross-sectional study of leptospira seroprevalence in humans, rats, mice, and dogs in a main tropical sea-port city. American Journal of Tropical Medicine and Hygiene 88: 178-183.

Golding GR, Bryden L, Levett PN, McDonald RR, Wong A, Graham MR, Tyler S, Van Domselaar G, Mabon P, Kent H, Butaye P, Smith TC, Kadlec K, Schwarz S, Weese SJ, Mulvey MR (2012) Whole-genome sequence of livestock-associated ST398 methicillin-resistant Staphylococcus aureus isolated from humans in Canada. Journal of Bacteriology 194:6627-6628.

Vidovic S, Thakur SD, Horsman GB, Levett PN, Anvari V, Dillon JA (2012) Longitudinal analysis of the evolution and dissemination of Neisseria gonorrhoeae strains (Saskatchewan, Canada, 2005 to 2008) reveals three major circulating strains and convergent evolution of ciprofloxacin and azithromycin resistance. Journal of Clinical Microbiology 50:3823-3830.

Mushanski LM, Brandt K, Coffin N, Levett PN, Horsman GB, Rank, EL (2012) Comparison of the BD Viper™ system with XTR™ technology to the Gen-Probe APTIMA COMBO 2 assay using the TIGRIS DTS system for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae in urine specimens, Sexually Transmitted Diseases 39:514-517.  

Golding GR, Levett PN, McDonald RR, Irvine J, Quinn B, Nsungu M, Woods S, Khan M, Ofner-Agostini M, Mulvey MR; Northern Antibiotic Resistance Partnership (2011) High rates of Staphylococcus aureus USA400 infection, Northern Canada. Emerging Infectious Diseases 17:722-725.

Antonishyn NA, Levett PN (2010) Molecular diagnostic assays for detection of viral respiratory pathogens in institutional outbreaks. Molecular Diagnosis and Therapy 14:283-93.

Galloway RL, Levett PN (2010) Application and validation of PFGE for serovar identification of Leptospira clinical isolates. PLoS Neglected Tropical Diseases 4: e824.

Golding GR, Levett PN, McDonald RR, Irvine J, Nsungu M, Woods S, Horbal A, Siemens CG, Khan M, Ofner-Agostini M, Mulvey MR and the Northern Antibiotic Resistance Partnership (2010) A comparison of risk factors associated with community associated methicillin-resistant and -susceptibleStaphylococcus aureus infections in remote communities. Epidemiology and Infection 138:730-737.

Golding GR, Bryden L, Levett PN, McDonald RR, Wong A, Wylie J, Graham MR, Tyler S, Van Domselaar G, Simor AE, Gravel D, Mulvey MR (2010) Livestock-associated methicillin-resistantStaphylococcus aureus sequence type 398 in humans, Canada. Emerging Infectious Diseases 16:587-594.

Bastien N, Antonishyn NA, Brandt K, Wong CE, Chokani K, Vegh N, Horsman GB, Tyler S, Graham MR, Plummer FA, Levett PN, Li Y (2010) Human infection with a triple reassortant swine influenza A (H1N1) containing hemagglutinin and neuraminidase of seasonal influenza. Clinical Infectious Diseases 201:1178-1182.

Levett PN, Edwards CN (2009) Leptospirosis. In: Bacterial Infections of Humans 4th edtn, edited by PS Brachman & E Abrutyn. New York: Springer, pp. 439-460.

Matthias MA, Ricaldi JN, Cespedes M, Diaz MM, Galloway RL, Saito M, Steigerwalt AG, Patra KP, Ore CV, Gotuzzo E, Gilman RH, Levett PN, Vinetz JM (2008) Human leptospirosis caused by a new, antigenically unique Leptospira associated with a Rattus species reservoir in the Peruvian Amazon. PLoS Neglected Tropical Diseases 2:e213.